Acute homing of bone marrow-derived mononuclear cells in intramyocardial vs. intracoronary transplantation.
Identifieur interne : 002046 ( Main/Exploration ); précédent : 002045; suivant : 002047Acute homing of bone marrow-derived mononuclear cells in intramyocardial vs. intracoronary transplantation.
Auteurs : RBID : pubmed:19544220English descriptors
- KwdEn :
- Animals, Bone Marrow Transplantation (methods), Cell Survival (drug effects), Hematopoietic Stem Cell Transplantation (methods), Hematopoietic Stem Cells (physiology), Indium Radioisotopes (adverse effects), Indium Radioisotopes (diagnostic use), Infusions, Intra-Arterial, Injections, Intramuscular, Myocardial Infarction (radionuclide imaging), Myocardial Infarction (surgery), Swine.
- MESH :
- chemical , adverse effects : Indium Radioisotopes.
- chemical , diagnostic use : Indium Radioisotopes.
- drug effects : Cell Survival.
- methods : Bone Marrow Transplantation, Hematopoietic Stem Cell Transplantation.
- physiology : Hematopoietic Stem Cells.
- radionuclide imaging : Myocardial Infarction.
- surgery : Myocardial Infarction.
- Animals, Infusions, Intra-Arterial, Injections, Intramuscular, Swine.
Abstract
Cell homing optimisation after transplantation is critical in myocardial infarction (MI) cell therapy.
DOI: 10.1080/14017430903045350
PubMed: 19544220
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Acute homing of bone marrow-derived mononuclear cells in intramyocardial vs. intracoronary transplantation.</title><author><name sortKey="M Kel, Jussi" uniqKey="M Kel J">Jussi Mäkelä</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Oulu University Hospital, University of Oulu and Clinical Research Center, 90221, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Surgery, Oulu University Hospital, University of Oulu and Clinical Research Center, 90221, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Anttila, Vesa" uniqKey="Anttila V">Vesa Anttila</name></author><author><name sortKey="Ylitalo, Kari" uniqKey="Ylitalo K">Kari Ylitalo</name></author><author><name sortKey="Takalo, Reijo" uniqKey="Takalo R">Reijo Takalo</name></author><author><name sortKey="Lehtonen, Siri" uniqKey="Lehtonen S">Siri Lehtonen</name></author><author><name sortKey="M Kikallio, Timo" uniqKey="M Kikallio T">Timo Mäkikallio</name></author><author><name sortKey="Niemel, Eija" uniqKey="Niemel E">Eija Niemelä</name></author><author><name sortKey="Dahlbacka, Sebastian" uniqKey="Dahlbacka S">Sebastian Dahlbacka</name></author><author><name sortKey="Tikkanen, Jonne" uniqKey="Tikkanen J">Jonne Tikkanen</name></author><author><name sortKey="Kiviluoma, Kai" uniqKey="Kiviluoma K">Kai Kiviluoma</name></author><author><name sortKey="Juvonen, Tatu" uniqKey="Juvonen T">Tatu Juvonen</name></author><author><name sortKey="Lehenkari, Petri" uniqKey="Lehenkari P">Petri Lehenkari</name></author></titleStmt><publicationStmt><date when="2009">2009</date><idno type="doi">10.1080/14017430903045350</idno><idno type="RBID">pubmed:19544220</idno><idno type="pmid">19544220</idno><idno type="wicri:Area/Main/Corpus">001E02</idno><idno type="wicri:Area/Main/Curation">001E02</idno><idno type="wicri:Area/Main/Exploration">002046</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Bone Marrow Transplantation (methods)</term><term>Cell Survival (drug effects)</term><term>Hematopoietic Stem Cell Transplantation (methods)</term><term>Hematopoietic Stem Cells (physiology)</term><term>Indium Radioisotopes (adverse effects)</term><term>Indium Radioisotopes (diagnostic use)</term><term>Infusions, Intra-Arterial</term><term>Injections, Intramuscular</term><term>Myocardial Infarction (radionuclide imaging)</term><term>Myocardial Infarction (surgery)</term><term>Swine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Indium Radioisotopes</term></keywords><keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Indium Radioisotopes</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Cell Survival</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Bone Marrow Transplantation</term><term>Hematopoietic Stem Cell Transplantation</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Hematopoietic Stem Cells</term></keywords><keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Myocardial Infarction</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Myocardial Infarction</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Infusions, Intra-Arterial</term><term>Injections, Intramuscular</term><term>Swine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Cell homing optimisation after transplantation is critical in myocardial infarction (MI) cell therapy.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">19544220</PMID><DateCreated><Year>2009</Year><Month>12</Month><Day>09</Day></DateCreated><DateCompleted><Year>2010</Year><Month>02</Month><Day>22</Day></DateCompleted><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1651-2006</ISSN><JournalIssue CitedMedium="Internet"><Volume>43</Volume><Issue>6</Issue><PubDate><Year>2009</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Scandinavian cardiovascular journal : SCJ</Title><ISOAbbreviation>Scand. Cardiovasc. J.</ISOAbbreviation></Journal><ArticleTitle>Acute homing of bone marrow-derived mononuclear cells in intramyocardial vs. intracoronary transplantation.</ArticleTitle><Pagination><MedlinePgn>366-73</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1080/14017430903045350</ELocationID><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">Cell homing optimisation after transplantation is critical in myocardial infarction (MI) cell therapy.</AbstractText><AbstractText Label="DESIGN" NlmCategory="METHODS">Eight pigs were randomized to receiving autologous purified (111)indium-labeled bone marrow mononuclear cells (BMMCs) (10(8) cells/2 ml) by intramyocardial (IM) (n=4) or by intracoronary (IC) (n=4) transplantation after 90 minutes occlusion of the CX-coronary artery. Dual isotope SPECT imaging was performed 2 and 24 hours postoperatively. Two animals were additionally analyzed on the sixth postoperative day. Tissue samples from the major organs were analyzed.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In SPECT imaging revealed that BMMCs administered using IM injection remained in the injured area. In contrast, minor proportion of IC transplanted cells remained in the myocardium, as most of the cells showed homing in the lungs. Analysis of the biopsies showed a seven-fold greater number of cells in the myocardium for the IM method and a 10-fold greater number of cells in the lungs in the IC group (p < 0.001).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">In producing persistently high cell homing at the infarction site, the IM transplantation is superior to the IC transplantation. However, the IC administration might be more specific in targeting injured capillaries and epithelial cells within the infarcted myocardium.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mäkelä</LastName><ForeName>Jussi</ForeName><Initials>J</Initials><Affiliation>Department of Surgery, Oulu University Hospital, University of Oulu and Clinical Research Center, 90221, Oulu, Finland.</Affiliation></Author><Author ValidYN="Y"><LastName>Anttila</LastName><ForeName>Vesa</ForeName><Initials>V</Initials></Author><Author ValidYN="Y"><LastName>Ylitalo</LastName><ForeName>Kari</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Takalo</LastName><ForeName>Reijo</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Lehtonen</LastName><ForeName>Siri</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Mäkikallio</LastName><ForeName>Timo</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Niemelä</LastName><ForeName>Eija</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Dahlbacka</LastName><ForeName>Sebastian</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Tikkanen</LastName><ForeName>Jonne</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Kiviluoma</LastName><ForeName>Kai</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Juvonen</LastName><ForeName>Tatu</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Lehenkari</LastName><ForeName>Petri</ForeName><Initials>P</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType>Comparative Study</PublicationType><PublicationType>Journal Article</PublicationType><PublicationType>Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Scand Cardiovasc J</MedlineTA><NlmUniqueID>9708377</NlmUniqueID><ISSNLinking>1401-7431</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Indium Radioisotopes</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Bone Marrow Transplantation</DescriptorName><QualifierName MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Cell Survival</DescriptorName><QualifierName MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Hematopoietic Stem Cell Transplantation</DescriptorName><QualifierName MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Hematopoietic Stem Cells</DescriptorName><QualifierName MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Indium Radioisotopes</DescriptorName><QualifierName MajorTopicYN="N">adverse effects</QualifierName><QualifierName MajorTopicYN="N">diagnostic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Infusions, Intra-Arterial</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Injections, Intramuscular</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Myocardial Infarction</DescriptorName><QualifierName MajorTopicYN="N">radionuclide imaging</QualifierName><QualifierName MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Swine</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year><Month>6</Month><Day>23</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2009</Year><Month>6</Month><Day>23</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2010</Year><Month>2</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pii">912577199</ArticleId><ArticleId IdType="doi">10.1080/14017430903045350</ArticleId><ArticleId IdType="pubmed">19544220</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=IndiumV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002046 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002046 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= *** parameter Area/wikiCode missing ***
|area= IndiumV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:19544220
|texte= Acute homing of bone marrow-derived mononuclear cells in intramyocardial vs. intracoronary transplantation.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:19544220" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a IndiumV2
| This area was generated with Dilib version V0.5.76. |  |